Lazaretto Creek is located on the edge of Tybee Island and can be accessed at the Lazaretto Creek Fishing Pier off U. S. Highway 80 or just over the Lazaretto Creek Bridge. It’s a great area for tourists and locals alike to stop and take in the salt marsh scenery. Georgia’s endangered shrimping industry is usually represented with a few boats and Captain Mike’s bright yellow Dolphin boats (since 1992) herald a boom in ecotourism. It’s really a nice contrast between old and new.