This lush stream rises in the Appalachian foothills a few miles north of Homer in Banks County and flows northeastward into Franklin County before turning southeastward and joining the Hudson River. All of these waterways feed the Broad River and its three forks.

Nails Creek was an important location in the development of industry in the region. J. D. Cromer had a sawmill, gristmill, and gin mill here in the late 19th century and this likely supported other small businesses, as well.