This beautiful church was organized no later than 1873 as Antioch Christian Church. It is affiliated with the Christian Church (Disciples of Christ) congregation. Its name was changed in 1900 to Guyton Christian Church. The congregation cemetery, located nearby on Little McCall Road, dates to 1873, but I do not know the date of this structure. It may be contemporary to the cemetery.

Guyton Historic District, National Register of Historic Places